Promoting the development of vaccines for low-income and middle-income countries
The challenge: unmet needs
There is an unacceptable toll of infectious diseases in developing countries. A major global effort is under way to accelerate the development and introduction of vaccines against such killers as diarrhoeal diseases, HIV/AIDS, malaria, tuberculosis among others. However, research and development (R&D) for vaccines and products primarily needed in the developing world attracts little interest from companies who are looking for returns on their investment. Some industrialized country governments do support R&D targeted at developing countries health needs, but the amount is minimal relative to the need, and is dwarfed by the amount spent on the needs of rich countries.
For example, less than $350 million is spent each year on HIV/AIDS prevention through vaccine research, compared with billions spent on R&D for drugs to treat the disease. And less than $60 million is spent on vaccine development against malaria , a disease that kills a million people a year.
The Task Forces contribution
The GAVI Board has asked the Financing Task Force to develop and implement appropriate financial and market-based strategies to accelerate the development, scale-up, and affordable pricing of three vaccines against major diseases in developing countries that are near to completion. These vaccines will protect infants from: pneumococcus, meningococcus A, and rotavirus. It is expected that this work will pave the way for future investments, which will accelerate the availability of vaccines against HIV, TB and malaria. Through this work, the FTF is specifically working to identify novel and creative financial strategies that will enhance the development, manufacture, and availability of priority vaccines that will reach the poor.
Financing Task Force
Identifying long-term financing options
Promoting the development of new vaccines for low-income and middle-income countries
Forecasting vaccine demand
Capacity Building in Financial Management
Accelerating new vaccines: an issues paper. Amie Batson, Sarah Glass and Ruth Levine. 2001
DRAFT for review and comment (Word - 337KB)
Annex (PPT - 30KB)
Accelerating an AIDS vaccine for developing countries: issues and options for the World Bank Martha Ainsworth, Amie Batson and Sandra Rosenhouse, 1999 (PDF - 57KB)
Accelerating an AIDS vaccine for developing countries: recommendations for the World Bank [February 28, Martha Ainsworth, Amie Batson, Geoffrey Lamb and Sandra Rosenhouse] (PDF - 84KB)
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